Search | WHO COVID-19 Research Database

Effects of Treatment of Coronavirus Disease 2019 With Convalescent Plasma in 25 B-Cell-Depleted Patients.

Gharbharan, Arvind; GeurtsvanKessel, Corine H; Jordans, Carlijn C E; Blaauw, Marc; van der Klift, Marjolein; Hassing, Robert-Jan; Smits-Zwinkels, Marijn; Meertens, Maaike; van den Hout, Ella C; de Man, Anne Marie; Hageman, Ilse; Bogers, Susanne; van der Schoot, C Ellen; Swaneveld, Francis; Anas, Adam A; Rokx, Casper; Rijnders, Bart J A.

Clin Infect Dis ; 74(7): 1271-1274, 2022 04 09.

Article in English | MEDLINE | ID: covidwho-1706426

ABSTRACT

Twenty-five B-cell-depleted patients (24 following anti-CD19/20 therapy) diagnosed with coronavirus disease 2019 had been symptomatic for a median of 26 days but remained antibody negative. All were treated with convalescent plasma with high neutralizing antibody titers. Twenty-one (84%) recovered, indicating the potential therapeutic effects of this therapy in this particular population.

Subject(s)

COVID-19 , Antibodies, Neutralizing/therapeutic use , Antibodies, Viral , COVID-19/therapy , Humans , Immunization, Passive , SARS-CoV-2 , COVID-19 Serotherapy

ABSTRACT

Subject(s)

SEND TO:

SELECTION OF CITATIONS

SEARCH DETAIL